Noni Research - Noni Fruit Research

Noni Research

Scientific enquiry into Noni could explore hundreds of specific claims made on behalf of this legendary plant. However, much of the scientific interest so far has focused on Noni’s potential in cancer treatment.

There are over 140 nutrients in Noni, many of which are not yet well-understood. These include some chemicals called anthraquinones and polysaccharides. Although research is limited and preliminary, some of these chemicals have inhibited processes associated with cancer within experimental conditions.

Interest in Noni’s role in cancer treatment is strong. As early as 1980, researchers were looking into its Beta sitosterol content, and in 1985 Dr. Heinicke began to publish work on Xeronine, which he theorizes is responsible for Noni’s traditional anti-cancer reputation.

Research into chemicals found in Morinda citrifolia, Noni’s botanical name, was already well underway in the 1970s. In fact, all the way back in 1920, a scientist named J. L. Simonsen published an article on the chemicals naturally found in Noni. However, while there’s been scientific interest in Noni for over 85 years, significant research took much longer to emerge.

In particular, a 1992 study was presented at the 83rd annual meeting of the American Association for Cancer Research. It examined Noni’s ability to prolong the lives of mice with lung cancer. The study presented some very interesting results, and interest in Noni’s potential anti-cancer role has deepened ever since.

A 1994 study by Hirazumi and Furusawa of the University of Hawaii, Honolulu concluded that Noni juice contains molecules called polysaccharides which possess anti-tumour activities for Lewis lung cancer. The researchers gave Noni to mice suffering from the disease in a controlled environment. Their results suggest that Noni’s polysaccharides attack cancer cells by activating the host’s immune system. This is in stark contrast to chemotherapy, which typically attacks cancer cells by introducing toxins to the host’s body.

Research has continued, producing several promising studies. Currently, an ongoing study by Dr. Brian Issell at the University of Hawaii at Manoa is testing Noni’s anti-cancer activity in human cancer patients. The study began in 2001 and will continue until at least 2006.

Researchers have examined some of Noni’s other properties as well. For example, a 1990 study at a French university examined the behavioural and analgesic properties of an extract of Noni roots. This study, as usual, found no evidence of toxicity from the Noni extract. At the same time, the study’s conclusions confirm Noni’s ability to relieve pain.

Noni has been a topic of scientific study for over 85 years. For the past 25 years, much of that research has focused on Noni’s anti-cancer properties. Several chemicals naturally occurring in Noni appear to combat cancer cells, although research is ongoing and it is far too early to recommend Noni in the treatment of cancer. Although many studies have yielded promising results, the FDA has determined that this evidence is limited and not conclusive. There are no known problems with toxicity, which means that there are few or no risks associated with taking Noni.

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Current Noni Research from the International Noni Communications Council

The Pharmacologically Active Ingredient of Noni
By R.M.Heinicke, University of Hawaii

The Little Know Noni
Hinduismtoday.com

Two Novel Glycosides from the Fruits of Morinda Citrifolia (Noni) Inhibit AP-1 Transactivation and Cell Transformation in the Mouse Epidermal JB6 Cell Line
Guangming Liu, Ann Bode, Wei-Ya Ma, Shengmin Sang, Chi-Tang Ho and Zigang Dong

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